B-Hbb-bt KO, Hbb-bs KO mice
March 19, 2024
Adult hemoglobin predominantly consists of Hemoglobin A, which is composed of two α-chains and two β-chains (α2β2). An imbalance between these α- and β-chains can result in the clinical manifestations of Thalassemia. This condition can be categorized into two primary types: α-thalassemia and β-thalassemia.
B-Cd11c-EGFP-DTR-Luc mice
March 15, 2024
B-hEGFR/hHER3 mice
March 15, 2024
B-hIL17RA/hIL17RB/hIL25 mice
March 15, 2024
B-hBCMA/hGPRC5D MC38
March 12, 2024
B-hTAU mice
March 11, 2024
B-hSORT1 mice plus
March 11, 2024
SORT1 (Sortilin) is a vital regulator that reduces PGRN levels in plasma and the brain by transporting it into cells for degradation. It’s also a transmembrane protein overexpressed in many cancers, playing a key role in protein internalization, sorting, and transportation. The coding sequences of human SORT1 were inserted to replace part of murine exon […]
B-hCLDN1 mice
March 11, 2024
B-hAPLP2 mice
March 11, 2024
B-hGCG mice
March 11, 2024
