B-hB7-H3 CT26.WT

January 14, 2022

The mouse B7-h3 gene was replaced by the human B7-H3 coding sequence in B-hB7-H3 CT26.WT cells. Human B7-H3 is highly expressed on the surface of B-hB7-H3 CT26.WT cells.

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B-hCD36 MC38

January 13, 2022

The mouse Cd36 gene was replaced by the human CD36 coding sequence in B-hCD36 MC38 cells. Human CD36 is highly expressed on the surface of B-hCD36 MC38 cells.

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B-hFGL1 MC38

January 13, 2022

The mouse Fgl1 gene was replaced by the human FGL1 coding sequence in B-hFGL1 MC38 cells. Human FGL1 is highly expressed and secreted by B-hFGL1 MC38 cells.

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B-hMERTK MC38

January 13, 2022

The exogenous promoter and chimeric MERTK coding sequence containing the human signal peptide, extracellular domain, transmembrane domain and mouse cytoplasmic domain was inserted to replace part of murine exon 1.

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B-hTROP2 MC38 plus

January 13, 2022

Expression cassettes containing the exogenous promoter and human TROP2 CDS were randomly inserted into the genome of B-hTROP2 MC38 plus cells. Human TROP2 was detected to be highly expressed on the surface of B-hTROP2 MC38 plus cells.

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B-hGPC3 MC38

January 13, 2022

The mouse Gpc3 gene was replaced by the human GPC3 coding sequence in B-hGPC3 MC38 cells. Human GPC3 is highly expressed on the surface of B-hGPC3 MC38 cells.

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B-hDLL3 MC38

January 13, 2022

The mouse Dll3 gene was replaced by the human DLL3 coding sequence in B-hDLL3 MC38 cells. Human DLL3 is highly expressed on the surface of B-hDLL3 MC38 cells.

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B-hC5 MC38

January 13, 2022

The CDS of human C5 was inserted to replace part of murine exon 2 in B-hC5 MC38 cells. Human C5 is highly expressed on the surface of B-hC5 MC38 cells.

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