B-HLA-A2.1/hNY-ESO-1 MC38

May 30, 2024

The B2M gene (Exon2 to Exon3) of mouse were replaced by the sequence encompassing the human B2M CDS, HLA-A*0201 gene that included leader sequence, α1 and α2 domains ligated to a fragment of the murine H-2Db gene containing the α3, transmembrane and cytoplasmic domains and NY-ESO-1 CDS. Human HLA-A2.1 is highly expressed on the surface […]

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