B-hEPHB3 mice
May 31, 2023
B-hAREG MC38
May 10, 2023
The mouse Areg gene was replaced by human AREG coding sequence in B-hAREG MC38 cells. Human AREG is highly expressed in the suspensions of B-hAREG MC38 cells.
B-hIL34 MC38
May 10, 2023
The mouse Il34 gene was replaced by human IL34 coding sequence in B-hIL34 MC38 cells. Human IL34 is highly expressed on B-hIL34 MC38 cells.
B-hPD-L1 plus/hTPBG MC38
May 10, 2023
The exogenous promoter and human PD-L1 CDS was inserted into the mouse Pd-l1 exon 3. The exogenous promoter and human TPBG CDS was inserted into mouse Tpbg locus site in B-hPD-L1 plus/hTPBG MC38. Human PD-L1 and TPBG were detected on the surface of B-hPD-L1 plus/hTPBG MC38 cells.
B-hCD19-luc GFP A20
May 10, 2023
The mouse Cd19 gene was replaced by human CD19 coding sequence in B-hCD19-luc GFP A20 cells. Human CD19 is highly expressed on the surface this cell. And this cell expresses firefly luciferase as a marker.
B-hSIGLEC15 CT26.WT
May 10, 2023
The mouse Siglec15 coding sequence was replaced by human SIGLEC15 coding sequence in B-hSIGLEC15 CT26.WT cells. Human SIGLEC15 is highly expressed on the surface of B-hSIGLEC15 CT26.WT cells.
B-hGPC3 CT26.WT
May 10, 2023
The human GPC3 coding sequence was inserted into the exon 1 of mouse Gpc3 in B-hGPC3 CT26.WT cells. Human GPC3 is highly expressed on the surface of B-hGPC3 CT26.WT cells.
B-hFOLR1 MC38
May 10, 2023
The human FOLR1 coding sequence was inserted into the exon 4 of mouse Folr1 in B-hFOLR1 MC38 cells. Human FOLR1 is highly expressed on the surface of B-hFOLR1 MC38 cells.
B-hPD-L1 CT26.WT
May 10, 2023
The mouse PD-L1 gene was replaced by human PD-L1 coding sequence in B-hPD-L1 CT26.WT cells. Human PD-L1 is highly expressed on the surface of B-hPD-L1 CT26.WT cells.
B-hPD-1/h4-1BB/hB7-H4 mice
May 10, 2023
