PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis
Yang, W., Guo, X., Tu, Z. et al. PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis. Protein Cell (2021). https://doi.org/10.1007/s13238-021-00888-x
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IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy
Chen, T., Ding, X., Liao, Q. et al. IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy. J Immunother Cancer. (2021). http://dx.doi.org/10.1136/jitc-2020-001647
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Hippocampal µ-opioid receptors on GABAergic neurons mediate stress-induced impairment of memory retrieval
Shi MM, Fan KM, Qiao YN, Xu JH, Qiu LJ, Li X, Liu Y, Qian ZQ, Wei CL, Han J, Fan J, Tian YF, Ren W, Liu ZQ. Hippocampal µ-opioid receptors on GABAergic neurons mediate stress-induced impairment of memory retrieval. Mol Psychiatry. 2020 May;25(5):977-992. doi: 10.1038/s41380-019-0435-z. Epub 2019 May 29. PMID: 31142818; PMCID: PMC7192851.
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Chitosan Hydrogel Enhances the Therapeutic Efficacy of Bone Marrow-Derived Mesenchymal Stem Cells for Myocardial Infarction by Alleviating Vascular Endothelial Cell Pyroptosis
Liu Y, Li P, Qiao C, Wu T, Sun X, Wen M, Zhang W. Chitosan Hydrogel Enhances the Therapeutic Efficacy of Bone Marrow-Derived Mesenchymal Stem Cells for Myocardial Infarction by Alleviating Vascular Endothelial Cell Pyroptosis. J Cardiovasc Pharmacol. 2020 Jan;75(1):75-83. doi: 10.1097/FJC.0000000000000760. PMID: 31663873; PMCID: PMC7668671.
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Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
Wang, J., Li, Y., Wang, P. et al. Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis. Cell Stem Cell. (2020). https://doi.org/10.1016/j.stem.2020.04.001
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Microglial P2Y12 receptor regulates ventral hippocampal CA1 neuronal excitability and innate fear in mice
Peng, J., Liu, Y., Umpierre, A.D. et al. Microglial P2Y12 receptor regulates ventral hippocampal CA1 neuronal excitability and innate fear in mice. Mol Brain. (2019). https://doi.org/10.1186/s13041-019-0492-x
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NRP-1 interacts with GIPC1 and α6/β4-integrins to increase YAP1/∆Np63α-dependent epidermal cancer stem cell survival
Grun, D., Adhikary, G., Eckert, R.L. NRP-1 interacts with GIPC1 and α6/β4-integrins to increase YAP1/∆Np63α-dependent epidermal cancer stem cell survival. Oncogene. (2018). https://doi.org/10.1038/s41388-018-0290-4
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CDYL Deficiency Disrupts Neuronal Migration and Increases Susceptibility to Epilepsy
Qin, R., Cao, S., Lyu, T. CDYL Deficiency Disrupts Neuronal Migration and Increases Susceptibility to Epilepsy. Cell Rep. (2017). https://doi.org/10.1016/j.celrep.2016.12.043
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Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF
Wang, X., Chen, H., Tian, R. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF. Nat Commun. (2017). doi: 10.1038/ncomms14091
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Generation of Hutat2:Fc Knockin Primary Human Monocytes Using CRISPR/Cas9
Wang, B., Zuo, J., Kang, W. Generation of Hutat2:Fc Knockin Primary Human Monocytes Using CRISPR/Cas9. Mol Ther Nuc Acids. (2018). https://doi.org/10.1016/j.omtn.2018.01.012
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