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BMI1 regulates multiple myeloma-associated macrophage’s pro-myeloma functions

Zhang, D., Huang, J., Wang, F. et al. BMI1 regulates multiple myeloma-associated macrophage’s pro-myeloma functions. Cell Death Dis 12, 495 (2021). https://doi.org/10.1038/s41419-021-03748-y

The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML

Qiao, X., Ma, J., Knight, T. et al. The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML. Blood Cancer J. 11, 111 (2021). https://doi.org/10.1038/s41408-021-00502-7

Targeting epidermal growth factor-overexpressing triple-negative breast cancer by natural killer cells expressing a specific chimeric antigen receptor

Liu Y, Zhou Y, Huang KH, Fang X, Li Y, Wang F, An L, Chen Q, Zhang Y, Shi A, Yu S, Zhang J. Targeting epidermal growth factor-overexpressing triple-negative breast cancer by natural killer cells expressing a specific chimeric antigen receptor. Cell Prolif. 2020 Aug;53(8):e12858. doi: 10.1111/cpr.12858. Epub 2020 Jun 27. PMID: 32592435; PMCID: PMC7445407.

Natural small molecule triptonide inhibits lethal acute myeloid leukemia with FLT3-ITD mutation by targeting Hedgehog/FLT3 signaling

Xu Y, Wang P, Li M, Wu Z, Li X, Shen J, Xu R. Natural small molecule triptonide inhibits lethal acute myeloid leukemia with FLT3-ITD mutation by targeting Hedgehog/FLT3 signaling. Biomed Pharmacother. 2021 Jan;133:111054. doi: 10.1016/j.biopha.2020.111054. Epub 2020 Nov 27. PMID: 33254022.

MUC1-Tn-targeting chimeric antigen receptor-modified Vγ9Vδ2 T cells with enhanced antigen-specific anti-tumor activity

Zhai X, You F, Xiang S, Jiang L, Chen D, Li Y, Fan S, Han Z, Zhang T, An G, Zhang B, Chen Y, Meng H, Yang L. MUC1-Tn-targeting chimeric antigen receptor-modified Vγ9Vδ2 T cells with enhanced antigen-specific anti-tumor activity. Am J Cancer Res. 2021 Jan 1;11(1):79-91. PMID: 33520361; PMCID: PMC7840711.

Endocytic pathway inhibition attenuates extracellular vesicle-induced reduction of chemosensitivity to bortezomib in multiple myeloma cells

Tu C, Du Z, Zhang H, Feng Y, Qi Y, Zheng Y, Liu J, Wang J. Endocytic pathway inhibition attenuates extracellular vesicle-induced reduction of chemosensitivity to bortezomib in multiple myeloma cells. Theranostics. 2021 Jan 1;11(5):2364-2380. doi: 10.7150/thno.47996. PMID: 33500730; PMCID: PMC7797667.

LunX-CAR T Cells as a Targeted Therapy for Non-Small Cell Lung Cancer

Hu Z, Zheng X, Jiao D, Zhou Y, Sun R, Wang B, Tian Z, Wei H. LunX-CAR T Cells as a Targeted Therapy for Non-Small Cell Lung Cancer. Mol Ther Oncolytics. 2020 Apr 21;17:361-370. doi: 10.1016/j.omto.2020.04.008. PMID: 32405534; PMCID: PMC7210386.

IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy

Chen T, Ding X, Liao Q, Gao N, Chen Y, Zhao C, Zhang X, Xu J. IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy. J Immunother Cancer. 2021 Jan;9(1):e001647. doi: 10.1136/jitc-2020-001647. PMID: 33504576; PMCID: PMC7843316.

Long-Term Engraftment Promotes Differentiation of Alveolar Epithelial Cells from Human Embryonic Stem Cell Derived Lung Organoids

Chen Y, Feng J, Zhao S, Han L, Yang H, Lin Y, Rong Z. Long-Term Engraftment Promotes Differentiation of Alveolar Epithelial Cells from Human Embryonic Stem Cell Derived Lung Organoids. Stem Cells Dev. 2018 Oct 1;27(19):1339-1349. doi: 10.1089/scd.2018.0042. Epub 2018 Aug 21. PMID: 30009668.

PD-L1/LAG-3 bispecific antibody enhances tumor-specific immunity

Jiang H, Ni H, Zhang P, Guo X, Wu M, Shen H, Wang J, Wu W, Wu Z, Ding J, Tang R, Zhou S, Chen B, Yu M, Jing H, Liu J. PD-L1/LAG-3 bispecific antibody enhances tumor-specific immunity. Oncoimmunology. 2021 Jun 24;10(1):1943180. doi: 10.1080/2162402X.2021.1943180. PMID: 34239776; PMCID: PMC8237984.