The ketogenic diet modulates tumor-associated neutrophil polarization via the AMOT-YAP/TAZ axis to inhibit colorectal cancer progression Used in this study: B-NDG mice Read more
Epigenetic Activation of the CMTM6-IGF2BP1-EP300 Positive Feedback Loop Drives Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma Used in this study: B-NDG mice Read more
Combined targeting of GPX4 and BCR-ABL tyrosine kinase selectively compromises BCR-ABL+ leukemia stem cells Used in this study: B-NDG mice Read more
Исследование защитной эффективности препарата КомбиМаб-2 против вируса иммунодефицита человека типа 1 на мышах, гуманизированных CD4+ Т-лимфоцитами Used in this study: B-NDG mice Read more
Development of a CD39 nanobody and its enhancement to chimeric antigen receptor T cells efficacy against ovarian cancer in preclinical studies Used in this study: B-hCD73/hCD39 mice Read more
Preclinical investigations and a first-in-human phase 1a trial of JS007, a novel anti-CTLA-4 antibody, in patients with advanced solid tumors Used in this study: B-hPD-1/hCTLA4 mice Read more
Topical delivery of human single-domain antibody targeting IL-33 for inhibiting mucosal inflammation Used in this study: B-hIL33 mice Read more
Discovery of a common light chain bispecific antibody targeting PD-1 and PD-L1 by Hybridoma-to-Phage-to-Yeast (H2PtY) platform Used in this study: B-hFcRn mice Read more
A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice Used in this study: B-hCD40 mice Read more
CD37 in acute myeloid leukemia: a novel surface target for drug delivery Used in this study: B-hCD37 mice Read more
