Anti-4-1BB×PD-L1 Bispecific Antibody Reinvigorates Tumor-Specific Exhausted CD8+ T Cells and Enhances the Efficacy of Anti-PD-1 Blockade

Jeon SH, You G, Park J, Chung Y, Park K, Kim H, Jeon J, Kim Y, Son WC, Jeong DS, Shin EC, Lee JY, Han DH, Jung J, Park SH. Anti-4-1BB×PD-L1 Bispecific Antibody Reinvigorates Tumor-Specific Exhausted CD8+ T Cells and Enhances the Efficacy of Anti-PD-1 Blockade. Clin Cancer Res. 2024 May 14.

Used in this study: B-hPD-1/hPD-L1/h4-1BB mice