EpCAM-targeting CAR-T cell immunotherapy is safe and efficacious for epithelial tumors

Li D, Guo X, Yang K, Yang Y, Zhou W, Huang Y, Liang X, Su J, Jiang L, Li J, Fu M, He H, Yang J, Shi H, Yang H, Tong A, Chen N, Hu J, Xu Q, Wei YQ, Wang W. EpCAM-targeting CAR-T cell immunotherapy is safe and efficacious for epithelial tumors. Sci Adv. 2023 Dec;9(48):eadg9721.

Used in this study:B-hEPCAM mice, B-NDG mice