Novel anti-4-1BB×PD-L1 bispecific antibody augments anti-tumor immunity through tumor-directed T-cell activation and checkpoint blockade

Authors: Seongju Jeong, Eunyoung Park, Hyung-Don Kim, Eunsil Sung, Hyunjoo Kim, Jaehyoung Jeon, Youngkwang Kim, Ui-Jung Jung, Yong-Gyu Son, Youngeun Hong, Hanbyul Lee, Shinai Lee, Yangmi Lim, Jonghwa Won, Minwoo Jeon, Shin Hwang, Lei Fang, Wenqing Jiang, Zhengyi Wang, Eui-Cheol Shin, Su-Hyung Park & Jaeho Jung

Citation: Jeong, S., Park, E., Kim, H-D. et al. Novel anti-4-1BB×PD-L1 bispecific antibody augments anti-tumor immunity through tumor-directed T-cell activation and checkpoint blockade. J Immunother Cancer. (2021). http://dx.doi.org/10.1136/jitc-2021-002428

Used in this study: humanized B-hPD-L1/h4-1BB mice