The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML
Qiao, X., Ma, J., Knight, T. et al. The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML. Blood Cancer J. 11, 111 (2021). https://doi.org/10.1038/s41408-021-00502-7
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Targeting epidermal growth factor-overexpressing triple-negative breast cancer by natural killer cells expressing a specific chimeric antigen receptor
Liu, Y., Zhou, Y., Huang, K-H. et al. Targeting epidermal growth factor-overexpressing triple-negative breast cancer by natural killer cells expressing a specific chimeric antigen receptor. Cell Prolif. (2020). https://doi.org/10.1111/cpr.12858
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Natural small molecule triptonide inhibits lethal acute myeloid leukemia with FLT3-ITD mutation by targeting Hedgehog/FLT3 signaling
Xu, Y., Wang, P., Li, M. et al. Natural small molecule triptonide inhibits lethal acute myeloid leukemia with FLT3-ITD mutation by targeting Hedgehog/FLT3 signaling. Biomed Pharmacother. (2021). https://doi.org/10.1016/j.biopha.2020.111054
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MUC1-Tn-targeting chimeric antigen receptor-modified Vγ9Vδ2 T cells with enhanced antigen-specific anti-tumor activity
Zhai, X., You, F., Xiang, S. et al. MUC1-Tn-targeting chimeric antigen receptor-modified Vγ9Vδ2 T cells with enhanced antigen-specific anti-tumor activity. Am J Cancer Res. (2021). PMID: 33520361
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Endocytic pathway inhibition attenuates extracellular vesicle-induced reduction of chemosensitivity to bortezomib in multiple myeloma cells
Tu, C., Du, Z., Zhang, H. et al. Endocytic pathway inhibition attenuates extracellular vesicle-induced reduction of chemosensitivity to bortezomib in multiple myeloma cells. Theranostics. (2021). https://www.thno.org/v11p2364.htm
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LunX-CAR T Cells as a Targeted Therapy for Non-Small Cell Lung Cancer
Hu, Z., Zheng, X., Jiao, D. et al. LunX-CAR T Cells as a Targeted Therapy for Non-Small Cell Lung Cancer. Mol Ther Oncolytics. (2020). https://doi.org/10.1016/j.omto.2020.04.008
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IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy
Chen, T., Ding, X., Liao, Q. et al. IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy. J Immunother Cancer. (2021). http://dx.doi.org/10.1136/jitc-2020-001647
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Long-Term Engraftment Promotes Differentiation of Alveolar Epithelial Cells from Human Embryonic Stem Cell Derived Lung Organoids
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PD-L1/LAG-3 bispecific antibody enhances tumor-specific immunity
Jiang, H., Ni, H., Zhang, P. et al. PD-L1/LAG3 bispecific antibody enhances tumor-specific immunity. Oncoimmunology. (2021). https://doi.org/10.1080/2162402X.2021.1943180
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Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer
Zhai, T., Wang, C., Xu, Y. et al. Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer. J Immunother Cancer. (2021). http://dx.doi.org/10.1136/jitc-2020-002131
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