Anti-BCMA-engineered Exosomes for Bortezomib Targeted Delivery in Multiple Myeloma Used in this study: B-NDG mice Read more
Microbiota regulates the TET1-mediated DNA hydroxymethylation program in innate lymphoid cell differentiation Used in this study: B-NDG mice Read more
Inhibition of HDAC2 sensitises antitumour therapy by promoting NLRP3/GSDMD-mediated pyroptosis in colorectal cancer Used in this study: B-NDG mice Read more
Characterization of a novel anti-PVRIG antibody with Fc-competent function that exerts strong antitumor effects via NK activation in preclinical models Used in this study:B-NDG hIL15 mice Read more
Activated Factor X delivered by Adeno-Associated virus significantly inhibited bleeding and alleviated hemophilia A/B arthropathy in hemophilia mice Used in this study:B-F9 KO mice Read more
IL-10 protects against OPC ferroptosis by regulating lipid reactive oxygen species levels post stroke Used in this study:B-Il10 KO mice Read more
Differential expression of interleukin-35 receptor distinguishes different subsets of granulocyte-macrophage-colony-stimulating factor-producing T helper cells in a mouse endometriosis model Used in this study: B-CD45.1 mice Read more
XFab-α4-1BB/CD40L fusion protein activates dendritic cells, improves expansion of antigen-specific T cells, and exhibits antitumour efficacy in multiple solid tumour models Used in this study:B-h4-1BB/hCD40 mice Read more
Antitumor activity of pegylated human interferon β as monotherapy or in combination with immune checkpoint inhibitors via tumor growth inhibition and dendritic cell activation Used in this study:B-hPD-1 mice Read more
Administration of a glypican-3 peptide increases the infiltration and cytotoxicity of CD8+ T cells against testicular yolk sac tumor, associated with enhancing the intratumoral cGAS/STING signaling Used in this study:B-HLA-A2.1 mice Read more
