Understanding interleukin 11 as a disease gene and therapeutic target Used in this study:B-hIL11/hIL11RA mice Read more
GB12-09, a bispecific antibody targeting IL4Rα and IL31Rα for atopic dermatitis therapy Used in this study:B-hIL4/hIL4RA mice(C.B6) Read more
ATG-101 is a tetravalent PD-L1×4-1BB bispecific antibody that stimulates anti-tumor immunity through PD-L1 blockade and PD-L1-directed 4-1BB activation Used in this study:B-h4-1BB mice Read more
Targeting CEACAM5-positive solid tumors using NILK-2401, a novel CEACAM5xCD47 κλ bispecific antibody Used in this study: B-hSIRPA/hCD47 mice Read more
Preclinical imaging evaluation of a bispecific antibody targeting hPD1/CTLA4 using humanized mice Used in this study: B-hPD-1/hCTLA4 mice, B-hPD-L1 MC38 Read more
BNST GABAergic neurons modulate wakefulness over sleep and anesthesia Used in this study:B-Grpr-iCre mice Read more
Function of gastrin-releasing peptide receptors in ocular itch transmission in the mouse trigeminal sensory system Used in this study:B-Grpr-iCre mice Read more
Re-analysis of single-cell transcriptomics reveals a critical role of macrophage-like smooth muscle cells in advanced atherosclerotic plaque Used in this study:B-CAG-Upar-tdTomato cKI mice Read more
A role for the cerebellum in motor-triggered alleviation of anxiety Used in this study:B-CAG-tdTomato cKI rats Read more
Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1 Used in this study:B-Cx3cr1-iCreERT2-EGFP mice Read more