Publications

A novel Tmem119-tdTomato reporter mouse model for studying microglia in the central nervous system

Ruan C, Sun L, Kroshilina A, Beckers L, De Jager P, Bradshaw EM, Hasson SA, Yang G, Elyaman W. A novel Tmem119-tdTomato reporter mouse model for studying microglia in the central nervous system. Brain Behav Immun. 2020 Jan;83:180-191. doi: 10.1016/j.bbi.2019.10.009. Epub 2019 Oct 8. PMID: 31604143.

Activation of G protein‐coupled receptor 30 protects neurons by regulating autophagy in astrocytes

Wang XS, Yue J, Hu LN, Tian Z, Zhang K, Yang L, Zhang HN, Guo YY, Feng B, Liu HY, Wu YM, Zhao MG, Liu SB. Activation of G protein-coupled receptor 30 protects neurons by regulating autophagy in astrocytes. Glia. 2020 Jan;68(1):27-43. doi: 10.1002/glia.23697. Epub 2019 Aug 19. PMID: 31429156.

Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b

Li W, Shen W, Zhang B, Tian K, Li Y, Mu L, Luo Z, Zhong X, Wu X, Liu Y, Zhou Y. Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b. Protein Cell. 2020 Mar;11(3):161-186. doi: 10.1007/s13238-019-0650-z. Epub 2019 Jul 17. PMID: 31317506; PMCID: PMC7026249.

Heterogeneity in endothelial cells and widespread venous arterialization during early vascular development in mammals

Hou, S., Li, Z., Dong, J. et al. Heterogeneity in endothelial cells and widespread venous arterialization during early vascular development in mammals. Cell Res 32, 333–348 (2022). https://doi.org/10.1038/s41422-022-00615-z

Functional comparison of SARS-CoV-2 with closely related pangolin and bat coronaviruses

Nie, J., Li, Q., Zhang, L. et al. Functional comparison of SARS-CoV-2 with closely related pangolin and bat coronaviruses. Cell Discov 7, 21 (2021). https://doi.org/10.1038/s41421-021-00256-3

SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape

Li Q, Nie J, Wu J, Zhang L, Ding R, Wang H, Zhang Y, Li T, Liu S, Zhang M, Zhao C, Liu H, Nie L, Qin H, Wang M, Lu Q, Li X, Liu J, Liang H, Shi Y, Shen Y, Xie L, Zhang L, Qu X, Xu W, Huang W, Wang Y. SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape. Cell. 2021 Apr 29;184(9):2362-2371.e9. doi: 10.1016/j.cell.2021.02.042. Epub 2021 Feb 23. PMID: 33735608; PMCID: PMC7901273.

A high-throughput single cell-based antibody discovery approach against the full-length SARS-CoV-2 spike protein suggests a lack of neutralizing antibodies targeting the highly conserved S2 domain

Used in this study: RenMab Mice

The establishment and application of CD3E humanized mice in immunotherapy

Zhang R, Zhang J, Zhou X, Zhao A, Yu C. The establishment and application of CD3E humanized mice in immunotherapy. Exp Anim. 2022 May 13. doi: 10.1538/expanim.22-0012. Epub ahead of print. PMID: 35570001.

CHD7 regulates bone-fat balance by suppressing PPAR-γ signaling

Liu, C., Xiong, Q., Li, Q. et al. CHD7 regulates bone-fat balance by suppressing PPAR-γ signaling. Nat Commun 13, 1989 (2022). https://doi.org/10.1038/s41467-022-29633-6

Management of prostate cancer by targeting 3βHSD1 after enzalutamide and abiraterone treatment

Zejie Mei, Tao Yang, Ying Liu, Yuanyuan Gao, Zemin Hou, Qian Zhuang, Dongyin He, Xuebin Zhang, Qilong Tan, Xuyou Zhu, Yingyi Qin, Xi Chen, Chengdang Xu, Cuidong Bian, Xinan Wang, Chenyang Wang, Denglong Wu, Shengsong Huang, Zhenfei Li, Management of prostate cancer by targeting 3βHSD1 after enzalutamide and abiraterone treatment, Cell Reports Medicine, 2022, 100608, ISSN 2666-3791, https://doi.org/10.1016/j.xcrm.2022.100608.