SIRT6 as a key event linking P53 and NRF2 counteracts APAP-induced hepatotoxicity through inhibiting oxidative stress and promoting hepatocyte proliferation

Authors: Yanying Zhou, Xiaomei Fan, Tingying Jiao, Wenzhou Li, Panpan Chen, Yiming Jiang, Jiahong Sun, Yixin Chen, Pan Chen, Lihuan Guan, Yajie Wen, Min Huang & Huichang Bi

Citation: Zhou, Y., Fan, X., Jiao, T. et al. SIRT6 as a key event linking P53 and NRF2 counteracts APAP-induced hepatotoxicity through inhibiting oxidative stress and promoting hepatocyte proliferation. Acta Pharm Sin B. (2021). https://doi.org/10.1016/j.apsb.2020.06.016

Used in this study: B-p53 knockout mice