Targeting macrophage checkpoint inhibitor SIRPα for anticancer therapy

Authors: Jie Liu, Seethu Xavy, Shirley Mihardja, Sharline Chen, Kavitha Sompalli, Dongdong Feng, Timothy Choi, Balaji Agoram, Ravindra Majeti, Irving L. Weissman & Jens-Peter Volkmer

Citation: Liu, J., Xavy, S., Mihardja, S. et al. Targeting macrophage checkpoint inhibitor SIRPα for anticancer therapy. JCI Insight. (2020). https://doi.org/10.1172/jci.insight.134728

Used in this study: double humanized B-hSIRPA/hCD47 mice; humanized immunodeficient B-NDG hSIRPA mice