Tag: TNFSF15

TL1A Pathway: Embarking on New Frontiers in IBD Therapy with Biocytogen’s Humanized Mice

January 28, 2025

On December 17, Sanofi’s TL1A antibody, duvakitug, demonstrated success in a Phase IIb study, improving clinical remission rates in patients with moderate to severe ulcerative colitis and Crohn’s disease. Currently, several TL1A inhibitors—including monoclonal and bispecific antibodies such as tulisokibart, PF-07261271, and FG-M701—are in development to address unmet needs in the treatment of inflammatory bowel […]

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