Researchers use gene-edited mouse models to study gene expression, investigate genetic diseases, conduct preclinical drug efficacy tests and more. In many studies, a mouse model expresses a gene mutation throughout its development and life, necessitating an inducible disease mouse model when researchers need more control over gene expression. Mouse models that provide this level of control are called conditional mouse models.
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Biocytogen has developed various Cre mice and DTR mice with expression in specific tissue and specific cell. Additionally, Biocytogen have developed reporter mice, which allow us to observe gene expression at the tissue or cellular level through experimental instruments when the reporter gene is expressed. This facilitates in vivo gene expression monitoring, cell labeling, and lineage tracing studies.
C57BL/6-Col1a1tm1(Alb-icre/ERT2)Bcgen/Bcgen • 110137
C57BL/6-Gt(ROSA)26Sortm1(CAG-icre/ERT2)Bcgen/Bcgen • 110147
