Speaker: Jenna Frame, PhD, Senior Scientist, Scientific Communications

• Humanized mouse models serve as powerful preclinical models to evaluate the in vivo efficacy of anti-human antibody candidates
• Biocytogen’s humanized IL4/IL4RA mice have been used to validate antibody drugs targeting IL4 signaling in the context of experimentally-induced asthma and atopic dermatitis
• Humanized IL-17 mice are a validated tool to assess anti-human IL-17 therapies and can be used as a model for experimentally-induced psoriasis