Advancing T cell Therapies Using B-hCD3 Mouse Models
November 4, 2021
Biocytogen’s humanized mice are rigorously designed and validated in the following ways to improve translation of CD3-targeting candidates: Expression (mRNA & flow cytometry), Immune cell frequency & maturation profiling and functional validation using reference antibodies whenever available.
Genome Engineering in Accelerating Discovery and Preclinical Applications
September 27, 2021
Use of Biocytogen’s CRISPR-based Extreme Genome Editing technology improves the efficiency of large fragment knock-in by up to 10-20 fold, meaning we can generate targeted cell lines, mouse and rat models in industry-leading timelines with a 98% success rate.
FcRn Therapies 2021 Conference: Humanized Mouse Models to Assess the In Vivo Efficacy of Antibody Therapeutics
March 25, 2021
Learn about the powerful models of Humanized mouse in IL4/IL4RA and IL-17 mice in various in-vivo settings
IO Summit Boston: Improve Translation of Humanized Animal Models for Immunotherapy
October 20, 2020
Learn about the new developments in humanized animal models to get ideas on how models can be applied to solve specific translational challenges.
Accelerating Therapeutic Antibody Discovery with Three Distinct Humanized Mouse Models
October 2, 2020
With a robust immune response, RenMab™ Mouse produces fully-human, functional antibodies of high antigen specificity and diverse epitopes.
Humanized Animal Models for Immunotherapy
October 2, 2020
Development and application of humanized animal models, which mimic human immunity and therapeutic targets, may provide promising solution to the challenges of preclinical translation
