B7-H3×4-1BB bispecific antibody augments antitumor immunity by enhancing terminally differentiated CD8+ tumor-infiltrating lymphocytes

B7-H3×4-1BB bispecific antibody augments antitumor immunity by enhancing terminally differentiated CD8+ tumor-infiltrating lymphocytes

Authors: Gihoon You, Yangsoon Lee, Yeon-Woo Kang, Han Wook Park, Kyeongsu Park, Hyekang Kim, Young-Min Kim, Sora Kim, Ji-Hae Kim, Dain Moon, Hyejin Chung, Wonjun Son, Ui-Jung Jung, Eunyoung Park, Shinai Lee, Yong-Gyu Son, Jaehyun Eom, Jonghwa Won, Yunji Park, Jaeho Jung & Seung-Woo Lee

Citation: You, G., Lee, Y., Kang, Y.-W. et al. B7-H3×4-1BB bispecific antibody augments antitumor immunity by enhancing terminally differentiated CD8+ tumor-infiltrating lymphocytes. Sci Adv. (2021). DOI: 10.1126/sciadv.aax3160

Used in this study: humanized B-h4-1BB mice

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