Basic Information
Strain name
C57BL/6-Gt(ROSA)26Sortm2(LPA)Bcgen/Bcgen
Common name
B-hLPA mice plus
Background
C57BL/6
Catalog number
112845
Aliases
LP; AK38; APOA
NCBI gene ID
-
Targeting strategy
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Gene targeting strategy for B-hLPA mice plus. The BAC contains human Lpa gene promoter and the full coding region genome sequences(include intron) as well as UTR was inserted into the Gt(ROSA)26Sor gene locus site.
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Protein expression analysis
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Strain specific Apo(a) protein expression analysis in B-hLPA mice plus by ELISA. Heterozygous B-hLPA mice plus (H/+), (n=3, female, 6-week-old). Human Apo(a) was exclusively detectable in heterozygous B-hLPA mice plus.
