Basic Information

Strain name
C57BL/6-Gt(ROSA)26Sortm2(LPA)Bcgen/Bcgen
Common name
B-hLPA mice plus
Background
C57BL/6
Catalog number
112845
Aliases
LP; AK38; APOA
NCBI gene ID

Targeting strategy

Gene targeting strategy for B-hLPA mice plus. The BAC contains human Lpa gene promoter and the full coding region genome sequences(include intron) as well as UTR was inserted into the Gt(ROSA)26Sor gene locus site.

Protein expression analysis

Strain specific Apo(a) protein expression analysis in B-hLPA mice plus by ELISA. Heterozygous B-hLPA mice plus (H/+), (n=3, female, 6-week-old). Human Apo(a) was exclusively detectable in heterozygous B-hLPA mice plus.

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