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The biologically functional identification of a novel TIM3-binding peptide P26 in vitro and in vivo

Used in this study: B-hPD-L1 MC38; B-hTIM3 Mice

Brain angiotensin type-1 and type-2 receptors: cellular locations under normal and hypertensive conditions

Used in this study: Gene Editing Services

Targeting Mechanistic Target of Rapamycin Complex 1 Restricts Proinflammatory T Cell Differentiation and Ameliorates Takayasu Arteritis

Used in this study: Immunodeficient B-NDG Mice

IKIP Negatively Regulates NF-κB Activation and Inflammation through Inhibition of IKKα/β Phosphorylation

Wu H, Liu H, Zhao X, Zheng Y, Liu B, Zhang L, Gao C. IKIP Negatively Regulates NF-κB Activation and Inflammation through Inhibition of IKKα/β Phosphorylation. J Immunol. 2020 Jan 15;204(2):418-427. doi: 10.4049/jimmunol.1900626. Epub 2019 Dec 11. PMID: 31826938.

Hic‐5 deficiency protects cerulein‐induced chronic pancreatitis via down‐regulation of the NF‐κB (p65)/IL‐6 signalling pathway

Chen H, Tan P, Qian B, Du Y, Wang A, Shi H, Huang Z, Huang S, Liang T, Fu W. Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway. J Cell Mol Med. 2020 Jan;24(2):1488-1503. doi: 10.1111/jcmm.14833. Epub 2019 Dec 3. PMID: 31797546; PMCID: PMC6991662.

MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer

Wang S, Huang J, Li C, Zhao L, Wong CC, Zhai J, Zhou Y, Deng W, Zeng Y, Gao S, Zhang Y, Wang G, Guan XY, Wei H, Wong SH, He HH, Shay JW, Yu J. MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer. Clin Cancer Res. 2020 Feb 1;26(3):746-757. doi: 10.1158/1078-0432.CCR-19-1611. Epub 2019 Oct 29. PMID: 31662330.

Epidermal growth factor receptor-extracellular-regulated kinase blockade upregulates TRIM32 signaling cascade and promotes neurogenesis after spinal cord injury

Xue W, Zhao Y, Xiao Z, Wu X, Ma D, Han J, Li X, Xue X, Yang Y, Fang Y, Fan C, Liu S, Xu B, Han S, Chen B, Zhang H, Fan Y, Liu W, Dong Q, Dai J. Epidermal growth factor receptor-extracellular-regulated kinase blockade upregulates TRIM32 signaling cascade and promotes neurogenesis after spinal cord injury. Stem Cells. 2020 Jan;38(1):118-133. doi: 10.1002/stem.3097. Epub 2019 Oct 17. PMID: 31621984.

A novel Tmem119-tdTomato reporter mouse model for studying microglia in the central nervous system

Ruan C, Sun L, Kroshilina A, Beckers L, De Jager P, Bradshaw EM, Hasson SA, Yang G, Elyaman W. A novel Tmem119-tdTomato reporter mouse model for studying microglia in the central nervous system. Brain Behav Immun. 2020 Jan;83:180-191. doi: 10.1016/j.bbi.2019.10.009. Epub 2019 Oct 8. PMID: 31604143.

Activation of G protein‐coupled receptor 30 protects neurons by regulating autophagy in astrocytes

Wang XS, Yue J, Hu LN, Tian Z, Zhang K, Yang L, Zhang HN, Guo YY, Feng B, Liu HY, Wu YM, Zhao MG, Liu SB. Activation of G protein-coupled receptor 30 protects neurons by regulating autophagy in astrocytes. Glia. 2020 Jan;68(1):27-43. doi: 10.1002/glia.23697. Epub 2019 Aug 19. PMID: 31429156.

Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b

Li W, Shen W, Zhang B, Tian K, Li Y, Mu L, Luo Z, Zhong X, Wu X, Liu Y, Zhou Y. Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b. Protein Cell. 2020 Mar;11(3):161-186. doi: 10.1007/s13238-019-0650-z. Epub 2019 Jul 17. PMID: 31317506; PMCID: PMC7026249.