Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine Used in this study: Gene Editing Services Read more
The Bispecific Tumor Antigen-Conditional 4-1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies Used in this study: B-h4-1BB mice Read more
Decoding Cinnabarinic Acid-Specific Stanniocalcin 2 Induction by Aryl Hydrocarbon Receptor Used in this study: Gene Editing Services Read more
Targeting circular RNA-MET for anti-angiogenesis treatment via inhibiting endothelial tip cell specialization Used in this study: B-Cdh5-iCreERT2 mice Read more
PPFIA1-targeting miR-181a mimic and saRNA overcome imatinib resistance in BCR-ABL1-independent chronic myeloid leukemia by suppressing leukemia stem cell regeneration Used in this study: Immunodeficient B-NDG Mice Read more
Targeting C/EBPα overcomes primary resistance and improves the efficacy of FLT3 inhibitors in acute myeloid leukaemia Used in this study: Immunodeficient B-NDG Mice Read more
Non-invasive activation of intratumoural gene editing for improved adoptive T-cell therapy in solid tumours Used in this study: B-NDG B2m KO Mice Plus Read more
Impact of stereopure chimeric backbone chemistries on the potency and durability of gene silencing by RNA interference Used in this study: Gene Editing Services Read more
A new NASH model in aged mice with rapid progression of steatohepatitis and fibrosis Used in this study: C57BL/6 mice Read more
Contribution of high-fat diet-induced PCSK9 upregulation to a mouse model of PCOS is mediated partly by SREBP2 Used in this study: Gene Editing Services Read more
