C57BL/6JNifdc-Cd5ltm1(CD5L)Bcgen/Bcgen • 112516
| Product name | B-hCD5L mice |
|---|---|
| Catalog number | 112516 |
| Strain name | C57BL/6JNifdc-Cd5ltm1(CD5L)Bcgen/Bcgen |
| Strain background | C57BL/6JNifdc |
| Aliases | CD5L: AIM, API6, CT-2, hAIM, PRO229, Spalpha, SP-ALPHA |
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Targeting strategyGene targeting strategy for B-hCD5L mice.
The exons 1~6 of mouse Cd5l gene that encode the full-length protein were replaced by human CD5L exons 1~6 in B-hCD5L mice.
Protein expression analysis
Strain specific CD5L expression analysis in homozygous B-hCD5L mice by ELISA. Plasma were isolated from wild-type C57BL/6 mice (+/+) and homozygous B-hCD5L mice (H/H) analyzed by ELISA with species-specific CD5L ELISA kit. Mouse CD5L was detectable in wild-type mice (A). Human CD5L was exclusively detectable in homozygous B-hCD5L mice but not in wild-type mice (B).
