B-hEPO mice

C57BL/6N-Epotm1(EPO)Bcgen/Bcgen • 112458

Order Product
B-hEPHB3 mice
B-hEPOR mice

B-hEPO mice

Product nameB-hEPO mice
Catalog number112458
Strain nameC57BL/6N-Epotm1(EPO)Bcgen/Bcgen
Strain backgroundC57BL/6N
NCBI gene ID2056 (Human)
AliasesDBAL, ECYT5, EP, MVCD2
Order Product

on this page

  • Targeting strategy
  • Phenotypic analysis

Posters

View All

    Publication

      Related Products

      View All
      Targeting strategy

      Gene targeting strategy for B-hEPO mice. The exons 1-5 of mouse Epo gene that encodes the full-length protein were replaced by human EPO exons 1-5 in B-hEPO mice.

      Protein expression analysis
      Strain specific EPO expression analysis in homozygous B-hEPO mice by ELISA. Serum were isolated from wild-type C57BL/6 mice (+/+) and homozygous B-hEPO mice (H/H) and analyzed by ELISA with species-specific EPO ELISA kit. Mouse EPO was detectable in wild-type mice (A). Human EPO was exclusively detectable in homozygous B-hEPO mice but not in wild-type mice (B).* 1 ng/mL=21.2 miu/L