C57BL/6N-Gdf8tm1(GDF8)Bcgen/Bcgen • 112413
| Product name | B-hGDF8 mice |
|---|---|
| Catalog number | 112413 |
| Strain name | C57BL/6N-Gdf8tm1(GDF8)Bcgen/Bcgen |
| Strain background | C57BL/6N |
| Aliases | GDF8: MSLHP, MSTN |
on this page
Targeting strategyGene targeting strategy for B-hGDF8 mice. The exons 1-3 of mouse Gdf8 gene that encodes the full-length protein were replaced by human GDF8 exons 1-3 in B-hGDF8 mice.
Protein expression analysis
Strain specific GDF8 expression analysis in homozygous B-hGDF8 mice by ELISA. Plasma was collected from wild-type C57BL/6 mice (+/+) and homozygous B-hGDF8 mice (H/H), and analyzed by ELISA. GDF8 proteins were both detectable in wild-type C57BL/6 and B-hGDF8 mice, as the ELISA kit cross recognized human and mouse GDF8.
mRNA expression analysis
