C57BL/6N-Il36atm1(IL36A)Bcgen/Bcgen • 110092
| Product name | B-hIL36A mice |
|---|---|
| Catalog number | 110092 |
| Strain name | C57BL/6N-Il36atm1(IL36A)Bcgen/Bcgen |
| Strain background | C57BL/6N |
| NCBI gene ID | 54448 |
| Aliases | IL36A, FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), IL1F6, interleukin 36 alpha |
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Tageting strategyGene targeting strategy for B-hIL36A mice.
The exon 2-5 of mouse Il36a gene that encodes the full-length protein were replaced by human IL36A exon 1-4 in B-hIL36A mice.
mRNA expression analysis
Strain specific analysis of IL36A gene expression in wild type (WT) mice and B-hIL36A mice by RT-PCR. Mouse Il36a mRNA was detectable only in stomach of WT mice (+/+). Human IL36A mRNA was detectable only in homozygous B-hIL36A mice (H/H) but not in WT mice (+/+).
Protein expression analysis
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