B-hITGA4 mice

C57BL/6-Itga4tm1(ITGA4)Bcgen/Bcgen • 110902

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B-hITGA4 mice

Product nameB-hITGA4 mice
Catalog number110902
Strain nameC57BL/6-Itga4tm1(ITGA4)Bcgen/Bcgen
Strain backgroundC57BL/6
NCBI gene ID16401
Aliasesintegrin subunit alpha 4, CD49D, IA4

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  • Phenotypic analysis

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mRNA expression analysis

Strain specific analysis of ITGA4 gene expression in wild-type mice and homozygous B-hITGA4 mice by RT-PCR. Mouse Itga4 mRNA was detectable in splenocytes of wild-type mice(+/+). Human ITGA4 mRNA was detectable in homozygous B-hITGA4 mice(H/H).

Protein expression analysis-DCs 

Strain specific ITGA4 expression analysis in homozygous B-hITGA4 mice by flow cytometry.   Splenocytes were collected from wild-type C57BL/6 mice(+/+) and homozygous B-hITGA4 mice(H/H). Mouse ITGA4 was exclusively detectable in wild-type C57BL/6 mice. Human ITGA4 was exclusively detectable in homozygous B-hITGA4 mice.

Protein expression analysis-NK cells

Strain specific ITGA4 expression analysis in homozygous B-hITGA4 mice by flow cytometry.   Splenocytes were collected from wild-type C57BL/6 mice(+/+) and homozygous B-hITGA4 mice(H/H). Mouse ITGA4 was exclusively detectable in wild-type C57BL/6 mice. Human ITGA4 was exclusively detectable in homozygous B-hITGA4 mice.

Protein expression analysis-Monocytes

Strain specific ITGA4 expression analysis in homozygous B-hITGA4 mice by flow cytometry.   Splenocytes were collected from wild-type C57BL/6 mice(+/+) and homozygous B-hITGA4 mice(H/H). Mouse ITGA4 was exclusively detectable in wild-type C57BL/6 mice. Human ITGA4 was exclusively detectable in homozygous B-hITGA4 mice.