B-hNCR2 mice

C57BL/6-Igs2tm1(NCR2)Bcgen/Bcgen • 111872

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B-hNCR3 mice

B-hNCR2 mice

Product nameB-hNCR2 mice
Catalog number111872
Strain nameC57BL/6-Igs2tm1(NCR2)Bcgen/Bcgen
Strain backgroundC57BL/6
AliasesLY95; CD336; NKP44; NK-p44; dJ149M18.1

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  • Phenotypic analysis

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Protein expression analysis in spleen NK cells

Strain specific NCR2 expression analysis in homozygous B-hNCR2 mice by flow cytometry. Splenocytes were collected from wild-type mice (+/+) and homozygous B-hNCR2 mice (H/H), and then were cultured for 4 days under 50 ng/mL hIL12 and hIL15 stimulation ex vivo. Flow cytometry was performed with anti-human NCR2 antibody to detect NCR2 expression. Human NCR2 was exclusively detectable in NK cells of homozygous B-hNCR2 mice.