B-Ifnar1 KO mice

C57BL/6N-Ifnar1tm1Bcgen/Bcgen • 111961

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B-Ifitm3 KO mice
B-Ifnar1 KO mice(129S2)

B-Ifnar1 KO mice

Product nameB-Ifnar1 KO mice
Catalog number111961
Strain nameC57BL/6N-Ifnar1tm1Bcgen/Bcgen
Strain backgroundC57BL/6N
AliasesAVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC
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  • Targeting strategy
  • Phenotypic analysis
Targeting strategy

Gene targeting strategy for B-Ifnar1 KO mice. The exons 1~11 and 3’UTR of mouse Ifnar1 gene were knocked out in B-Ifnar1 KO mice.

Protein expression analysis
IFNAR1 expression analysis in wild-type C57BL/6N and B-Ifnar1 KO mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6N and B-Ifnar1 KO mice. Mouse IFNAR1 was detectable in B cells, T cells, NK cells, DC cells, monocytes, macrophages and granulocytes of wild-type mice, but not in B-Ifnar1 KO mice.