Results
Orthotopic Gastric cancer Model: B-CMV-Luc SNU-5+ B-NDG mice (orthotopic)
| Study ID: |
Groups |
Animal strain |
Sex |
Cell line |
The amount of
cells Inoculated |
The Volume
of cells |
Animal number |
Remarks |
| 24P071549 |
G1 |
B-NDG mice |
F |
B-CMV-Luc SNU-5 |
1×105 |
0.02ml/mice |
6 |
Orthotopic |
| G2 |
B-NDG mice |
F |
B-CMV-Luc SNU-5 |
5×105 |
0.02ml/mice |
6 |
Orthotopic |
| G3 |
B-NDG mice |
F |
B-CMV-Luc SNU-5 |
5×106 |
0.2ml/mice |
6 |
Subcutaneously on the right flank |
Establishment of orthotopic gastric cancer model.
The B-NDG mice (F, n=6) were inoculated with B-CMV-Luc SNU-5 cell suspension (1×10⁵, 5×10⁵, 5×10⁶) at the head of the pancreas or subcutaneously on the right flank. And the body weight and tumor fluorescence signal of the mice were recorded weekly. The results showed that the fluorescence signal gradually increased. This indicates that the cell line was successfully constructed as an orthotopic tumor model.
