Inflammation Models
Autoimmune diseases and other inflammatory disorders are mediated by dysfunction of the body’s immune system, typically in the form of hypersensitivity. These disorders are subject to intensive research and drug development efforts, and require extensive study in mouse models of inflammation. Biocytogen provides robust inflammation models, including those designed to experimentally model experimental autoimmune encephalomyelitis (EAE), psoriasis, asthma, and other diseases in mice. Novel anti-human inflammatory modulators can also be tested in our humanized cytokine/cytokine receptor mouse models. These mouse models of inflammation allow researchers to evaluate the preclinical efficacy of therapeutics against specific human targets in mice critical to the underlying molecular mechanisms of autoimmune and inflammatory diseases.
For a full list of our humanized cytokine models, click here.
Watch our recent webinars:
Inflammatory Disease Modeling for Preclinical Studies
Joint, Lung, and Urinary Disease Models Offered at Biocytogen
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Skin disease models
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Delayed type hypersensitivity: OXA, KLH
Pruritus: Wound healing (in development)
Alopecia Areata: IMQ (in development)
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Respiratory disease models
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Digestive disease models
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Ulcerative enteritis: DSS, TNBS
Crohn’s disease: T cell transfer model (in development)
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Joint injury disease models
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Nervous disease models
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Ischemic stroke: MCAO model (in development)
Inflammatory pain: Plantar pain measuring instrument (in development)
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Urinary disease models
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Systemic Lupus Erythematosus: Pristane
Nephritis: POP model (in development)