RenMice™: Powerful Fully Human Therapeutic Antibody Discovery Platforms
Biocytogen’s RenMab™, RenLite®, and RenNano® humanized mice are powerful platforms for fully human therapeutic antibody discovery. The RenMab™ model, our best-in-class humanized antibody mouse, is ideal for the discovery of fully human therapeutic antibodies. The RenLite® mouse model is specially designed for bispecific and multispecific antibody discovery, as the common light chain eliminates chain mispairing issues during bispecific antibody development. These models have also been further modified to support the discovery of TCR-mimic antibodies and anti-GPCR antibodies. Learn More:
Our recently introduced RenNano® mice generate fully human heavy-chain-only antibodies, which allows for specialized therapeutic applications requiring nanobody or HCAbs.
Altogether, these fully human antibody mouse models allow for natural in vivo selection and affinity maturation, ensuring maximum developability of your anti-human therapeutic antibody.
With the development of these models, Biocytogen has launched 6 therapeutic antibody discovery platforms. To learn more about how our models and platforms can support your therapeutic drug discovery, visit the pages linked below or contact us.