Cytokines play an important role in regulating the body’s immune, hematopoietic, nervous, and endocrine systems. Cytokine antibodies in drug development have demonstrated clinical significance in treating autoimmune and other inflammatory diseases. Backed by detailed investigation and careful design, Biocytogen presents a series of mouse models with humanized cytokines and/or cytokine receptors for preclinical evaluation of novel anti-human immunotherapies.
Humanized Cytokine Mice
| Product | Product No | Background |
|---|---|---|
| B-hALB mice | 110960 | C57BL/6 |
| B-hANGPTL4 mice | 111085 | C57BL/6 |
| B-hANGPTL8 mice | 111230 | C57BL/6 |
| B-hC5/hC5AR1 mice | 121215 | C57BL/6 |
| B-hCCN1 mice | 111235 | C57BL/6 |
| B-hCCN2 mice | 111523 | C57BL/6 |
| B-hCD14 mice | 111130 | C57BL/6 |
| B-hCSF1R mice | 110035 | C57BL/6 |
| B-hCXCL13 mice | 111136 | C57BL/6 |
| B-hGDF15 mice | 111201 | C57BL/6 |
| B-hIFNGR1 mice | 110804 | C57BL/6 |
| B-hIFNGR2 mice | 110803 | C57BL/6 |
| B-hIGFBP2 mice | 110987 | C57BL/6 |
| B-hIL10 mice | 110060 | C57BL/6 |
| B-hIL10/hIL10RA mice | 120750 | C57BL/6 |
| B-hIL10RA mice | 110083 | C57BL/6 |
| B-hIL10RB mice | 110773 | C57BL/6 |
| B-hIL11 mice | 110079 | C57BL/6 |
| B-hIL11/hIL11RA mice | 111865 | C57BL/6 |
| B-hIL11RA mice | 110879 | C57BL/6 |
| B-hIL12A/hIL12B/hIL12RB1/hIL12RB2 mice | 140575 | C57BL/6 |
| B-hIL13 mice | 110058 | C57BL/6 |
| B-hIL15RA mice | 110112 | C57BL/6 |
| B-hIL17A Mice | 110053 | C57BL/6 |
| B-hIL17A/hIL17F mice | 120554 | C57BL/6 |
| B-hIL17RA mice | 110054 | C57BL/6 |
| B-hIL17RB mice | 110090 | C57BL/6 |
| B-hIL1A mice | 110073 | C57BL/6 |
| B-hIL1B mice | 110075 | C57BL/6 |
| B-hIL1RAcP mice | 110072 | C57BL/6 |
| B-hIL2 mice | 110085 | C57BL/6 |
| B-hIL2/hIL2RA/hIL2RB mice | 131076 | C57BL/6 |
| B-hIL21R mice | 110766 | C57BL/6 |
| B-hIL23A/hIL12B mice | 120553 | C57BL/6 |
| B-hIL27 mice | 110763 | C57BL/6 |
| B-hIL27RA mice | 110765 | C57BL/6 |
| B-hIL2RA mice | 110066 | C57BL/6 |
| B-hIL2RB mice | 110737 | C57BL/6 |
| B-hIL2RB/IL2RG mice | 111850 | C57BL/6 |
| B-hIL2RG mice | 110087 | C57BL/6 |
| B-hIL3 mice | 110080 | C57BL/6 |
| B-hIL31/hIL31RA mice | 120745 | C57BL/6 |
| B-hIL33 mice | 110055 | C57BL/6 |
| B-hIL33/hTSLP/hTSLPR mice | 111867 | C57BL/6 |
| B-hIL36A mice | 110092 | C57BL/6 |
| B-hIL36R mice | 110084 | C57BL/6 |
| B-hIL4 mice | 110064 | C57BL/6 |
| B-hIL4/hIL4RA mice | 120551 | C57BL/6 |
| B-hIL4/hIL4RA/hIL13 mice | 131037 | C57BL/6 |
| B-hIL6/hIL6R mice | 120557 | C57BL/6 |
| B-hIL9R mice | 110761 | C57BL/6 |
| B-hLTA/hTNFA/hLTB mice | 130769 | C57BL/6 |
| B-hOSMR mice | 111859 | C57BL/6 |
| B-hPAI1 mice | 111119 | C57BL/6 |
| B-hPCSK9 mice | 110928 | C57BL/6 |
| B-hPD-1/hPCSK9 mice | 111861 | C57BL/6 |
| B-hPD-1/hPD-L1/hCSF1/hCSF1R mice | 111854 | C57BL/6 |
| B-hPD-1/hPD-L1/hIL1B mice | 131619 | C57BL/6 |
| B-hRSPO1 mice | 110900 | C57BL/6 |
| B-hSORT1 mice | 111158 | C57BL/6 |
| B-hSOST mice | 110111 | C57BL/6 |
| B-hSPP1 mice | 111087 | C57BL/6 |
| B-hTNFA mice | 110002 | C57BL/6 |
| B-hTNFA/hIL17A mice | 120548 | C57BL/6 |
| B-hTNFA/hTNFR2 mice | 120749 | C57BL/6 |
| B-hTNFR2 mice | 110032 | C57BL/6 |
| B-hTSLP mice | 110834 | C57BL/6 |
| B-hTSLP/hTSLPR mice | 121269 | C57BL/6 |
