Humanized Cytokine Mice

Cytokines play an important role in regulating the body’s immune, hematopoietic, nervous, and endocrine systems. Cytokine antibodies in drug development have demonstrated clinical significance in treating autoimmune and other inflammatory diseases. Backed by detailed investigation and careful design, Biocytogen presents a series of mouse models with humanized cytokines and/or cytokine receptors for preclinical evaluation of novel anti-human immunotherapies.

Humanized Cytokine Mice

Product Product No Background
B-Tg(hIFNG/hIL26) mice 131596 C57BL/6N
B-Tg(hIL8) mice 110832 C57BL/6N
B-hADIPOQ mice 111594 C57BL/6
B-hADM mice 111150 C57BL/6N
B-hAFP mice 111622 C57BL/6N
B-hALB mice 110960 C57BL/6J
B-hANG2 mice 112028 C57BL/6
B-hANGPTL3 mice 112224 C57BL/6
B-hANGPTL3 mice plus 112523 C57BL/6N
B-hANGPTL4 mice 111085 C57BL/6N
B-hANGPTL4 mice plus 112746 C57BL/6JNifdc
B-hANGPTL8 mice 111230 C57BL/6N
B-hBAFF mice 110830 C57BL/6
B-hBAFF/hBAFFR mice 111921 C57BL/6
B-hBAFFR mice 111140 C57BL/6N
B-hC3 mice 112467 C57BL/6N
B-hC5/hC5AR1 mice 121215 C57BL/6
B-hCCL11 mice 111404 C57BL/6N
B-hCCL2 mice 111102 C57BL/6N
B-hCCL20 mice 110854 C57BL/6N
B-hCCL22 mice 110817 C57BL/6
B-hCCL24 mice 111396 C57BL/6N
B-hCCL3 mice 111439 C57BL/6N
B-hCCL4 mice 111440 C57BL/6JNifdc
B-hCCL5 mice 111192 C57BL/6N
B-hCCN1 mice 111235 C57BL/6N
B-hCCN2 mice 111523 C57BL/6N
B-hCCN4 mice 111237 C57BL/6
B-hCD14 mice 111130 C57BL/6N
B-hCD59 mice 111427 C57BL/6
B-hCD5L mice 112516 C57BL/6JNifdc
B-hCDH17 mice 111593 C57BL/6
B-hCETP mice 111443 C57BL/6
B-hCFB mice 111006 C57BL/6N
B-hCFD mice 111005 C57BL/6N
B-hCSF1R mice 110035 C57BL/6
B-hCSF2RB mice 110735 C57BL/6
B-hCSF3 mice 111899 C57BL/6N
B-hCXCL1 mice 111395 C57BL/6N
B-hCXCL10 mice 111354 C57BL/6N
B-hCXCL13 mice 111136 C57BL/6N
B-hCXCL16 mice 111193 C57BL/6N
B-hCXCL3 mice 112600 C57BL/6N
B-hCXCL7 mice 112404 C57BL/6N
B-hCXCL7/hCXCL4 mice 112063 C57BL/6N
B-hDKK1 mice 111277 C57BL/6N
B-hEPO mice 112458 C57BL/6N
B-hFAP/hIFNGR1/hIFNG/hIFNGR2 mice 113111 C57BL/6
B-hFCER1A mice 111090 C57BL/6N
B-hFGF21 mice 112156 C57BL/6N
B-hFGFR3 mice 112158 C57BL/6N
B-hGDF15 mice 111201 C57BL/6N
B-hGDF8 mice 112413 C57BL/6N
B-hGEP mice 112346 C57BL/6N
B-hGFRAL mice 111202 C57BL/6
B-hGHRL mice 111092 C57BL/6N
B-hGRP mice 111902 C57BL/6
B-hHAMP mice 111019 C57BL/6N
B-hICOS mice 112105 C57BL/6
B-hIFNAR1/hIFNAR2 mice 112650 C57BL/6N
B-hIFNAR2 mice 112400 C57BL/6N
B-hIFNB1 mice 111210 C57BL/6N
B-hIFNGR1 mice 110804 C57BL/6
B-hIFNGR1/hIFNG mice 120819 C57BL/6
B-hIFNGR1/hIFNG/hIFNGR2 mice 130949 C57BL/6
B-hIFNGR2 mice 110803 C57BL/6
B-hIGF1R mice 111274 C57BL/6
B-hIGF2R mice 110986 C57BL/6
B-hIGFBP2 mice 110987 C57BL/6J
B-hIGFBP7 mice 111976 C57BL/6N
B-hIL10 mice 110060 C57BL/6
B-hIL10/hIL10RA mice 120750 C57BL/6
B-hIL10/hIL10RA/hIL10RB mice 112664 C57BL/6
B-hIL10RA mice 110083 C57BL/6
B-hIL10RA/hIL10RB mice 111871 C57BL/6
B-hIL10RA/hIL2RG mice 111870 C57BL/6
B-hIL10RB mice 110773 C57BL/6
B-hIL11 mice 110079 C57BL/6
B-hIL11/hIL11RA mice 111865 C57BL/6
B-hIL11RA mice 110879 C57BL/6
B-hIL12A/hIL12B/hIL12RB1/hIL12RB2 mice 140575 C57BL/6
B-hIL13 mice 110058 C57BL/6
B-hIL13RA1 mice 111717 C57BL/6
B-hIL15/hIL15RA mice 121217 C57BL/6
B-hIL15RA mice 110112 C57BL/6
B-hIL17A Mice 110053 C57BL/6
B-hIL17A/hIL17F mice 120554 C57BL/6
B-hIL17B mice 110089 C57BL/6
B-hIL17RA mice 110054 C57BL/6J
B-hIL17RA/hIL17RB mice 112896 C57BL/6
B-hIL17RA/hIL17RC mice 120555 C57BL/6
B-hIL17RB mice 110090 C57BL/6J
B-hIL17RB/hIL25 mice 120560 C57BL/6
B-hIL18 mice 111276 C57BL/6N
B-hIL18BP mice 112360 C57BL/6
B-hIL19 mice 111597 C57BL/6N
B-hIL1B mice 110075 C57BL/6
B-hIL1RAcP mice 110072 C57BL/6J
B-hIL2 mice 110085 C57BL/6
B-hIL2/hIL2RA/hIL2RB mice 131076 C57BL/6
B-hIL2/hIL2RA/hIL2RB/hIL2RG mice 112748 C57BL/6
B-hIL20 mice 111995 C57BL/6N
B-hIL21R mice 110766 C57BL/6
B-hIL21R/hIL2RG mice 112925 C57BL/6
B-hIL22/hIL22RA1 mice 121704 C57BL/6
B-hIL22RA1/hIL10RB mice 112331 C57BL/6
B-hIL23A/hIL12B mice 120553 C57BL/6
B-hIL27 mice 110763 C57BL/6
B-hIL27/hIL27RA mice 121566 C57BL/6
B-hIL27RA mice 110765 C57BL/6J
B-hIL2RA mice 110066 C57BL/6
B-hIL2RB mice 110737 C57BL/6
B-hIL2RB/hIL15 mice 111945 C57BL/6
B-hIL2RB/hIL2RG mice 111850 C57BL/6
B-hIL2RB/hIL2RG/hIL15/hIL15RA mice 111866 C57BL/6
B-hIL2RG mice 110087 C57BL/6N
B-hIL3 mice 110080 C57BL/6
B-hIL31/hIL31RA/hOSM/hOSMR mice 112647 C57BL/6
B-hIL31/hIL31RA/hOSMR mice 130746 C57BL/6
B-hIL31/hIL31RA/hOSMR/hIL4/hIL4RA mice 112908 C57BL/6
B-hIL33 mice 110055 C57BL/6
B-hIL33/hTSLP/hTSLPR mice 111867 C57BL/6
B-hIL33/hTSLP/hTSLPR mice plus 112935 C57BL/6
B-hIL36A mice 110092 C57BL/6N
B-hIL36R mice 110084 C57BL/6J
B-hIL36R/hIL1RACP mice 112383 C57BL/6
B-hIL4/hIL4RA mice 120551 C57BL/6
B-hIL4/hIL4RA mice(C.B6) 111889 BALB/cCrSlcNifdc.C57BL/6JNifdc
B-hIL4/hIL4RA/hIL13 mice 131037 C57BL/6
B-hIL4/hIL4RA/hTSLP/hTSLPR mice 112954 C57BL/6
B-hIL4/hIL4RA/hTSLP/hTSLPR plus mice 112846 C57BL/6
B-hIL5 mice 110071 C57BL/6J
B-hIL5/hIL5RA mice 111932 C57BL/6N
B-hIL6/hIL6R mice 120557 C57BL/6
B-hIL6ST mice 111200 C57BL/6
B-hIL7R mice 110082 C57BL/6
B-hIL9 mice 110760 C57BL/6
B-hIL9R mice 110761 C57BL/6J
B-hINHBE mice 112773 C57BL/6JNifdc
B-hIgE/hFCER1A mice 111891 C57BL/6N
B-hKLK2/hKLK3 mice 112233 C57BL/6
B-hLAIR1 mice 111660 C57BL/6N
B-hLIF mice 111199 C57BL/6N
B-hLPA mice 112723 C57BL/6
B-hLTA/hTNFA/hLTB mice 130769 C57BL/6J
B-hLYPD3 mice 111661 C57BL/6
B-hMAG mice 111033 C57BL/6N
B-hMASP2 mice 110872 C57BL/6N
B-hMIF mice 111047 C57BL/6N
B-hOSM/hOSMR mice 121329 C57BL/6
B-hPAI1 mice 111119 C57BL/6N
B-hPCSK9 mice 110928 C57BL/6
B-hPCSK9 mice plus 112751 C57BL/6
B-hPD-1/hPCSK9 mice 111861 C57BL/6
B-hPD-1/hPD-L1/hCSF1/hCSF1R mice 111854 C57BL/6
B-hPD-1/hPD-L1/hIL1B mice 131619 C57BL/6
B-hPD-1/hPD-L1/hVEGFA mice 112706 C57BL/6
B-hPD-1/hPD-L1/hVEGFR2 mice 112494 C57BL/6
B-hPTHRP mice 111017 C57BL/6N
B-hRNASE4 mice 112595 C57BL/6
B-hRSPO1 mice 110900 C57BL/6N
B-hRSPO3 mice 110883 C57BL/6
B-hS100A9 mice 111224 C57BL/6N
B-hS100A9/hS100A8 mice 121444 C57BL/6N
B-hSELE/hSELL mice 121056 C57BL/6
B-hSOST mice 110111 C57BL/6
B-hSPP1 mice 111087 C57BL/6N
B-hTDGF1 mice 111225 C57BL/6N
B-hTEK mice 111106 C57BL/6
B-hTGM2 mice 111028 C57BL/6
B-hTNFA mice 110002 C57BL/6
B-hTNFA/hIL17A mice 120548 C57BL/6
B-hTNFA/hTNFR2 mice 120749 C57BL/6
B-hTNFR2 mice 110032 C57BL/6
B-hTNFR2/hTNFR1/hLTBR mice 140801 C57BL/6
B-hTSLP/hTSLPR mice 121269 C57BL/6
B-hTSLP/hTSLPR mice plus 112744 C57BL/6
B-hTSLP/hTSLPR mice(C) 112923 BALB/cCrSlcNifdc
B-hTWEAK/hAPRIL mice 110805 C57BL/6
B-hVEGFA mice 110822 C57BL/6
B-hVEGFA/hANG2 mice 113125 C57BL/6
B-hVEGFR1 mice 110981 C57BL/6J
B-hVWF mice 110907 C57BL/6
B-hWNT3A mice 111021 C57BL/6J
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