Cytokines play an important role in regulating the body’s immune, hematopoietic, nervous, and endocrine systems. Cytokine antibodies in drug development have demonstrated positive clinical significance for treating autoimmune and other inflammatory diseases. The mechanisms and signal pathways of cytokines in the body are complex. Backed by detailed investigation and careful design, Biocytogen presents a series of mice models for preclinical evaluation of immunotherapy drugs with humanized cytokines and their receptors.
Humanized Cytokines Mice
| Product | Product No | Background |
|---|---|---|
| B-hALB mice | 110960 | C57BL/6 |
| B-hCSF1R mice | 110035 | C57BL/6 |
| B-hIGFBP2 mice | 110987 | C57BL/6 |
| B-hIL10 mice | 110060 | C57BL/6 |
| B-hIL12A/hIL12B/hIL12RB1/hIL12RB2 mice | 140575 | C57BL/6 |
| B-hIL13 mice | 110058 | C57BL/6 |
| B-hIL15RA mice | 110112 | C57BL/6 |
| B-hIL17A Mice | 110053 | C57BL/6 |
| B-hIL17A/hIL17F mice | 120554 | C57BL/6 |
| B-hIL17RA mice | 110054 | C57BL/6 |
| B-hIL17RB mice | 110090 | C57BL/6 |
| B-hIL1A mice | 110073 | C57BL/6 |
| B-hIL1B mice | 110075 | C57BL/6 |
| B-hIL1RAcP mice | 110072 | C57BL/6 |
| B-hIL2 mice | 110085 | C57BL/6 |
| B-hIL2/hIL2RA/hIL2RB mice | 131076 | C57BL/6 |
| B-hIL21R mice | 110766 | C57BL/6 |
| B-hIL23A/hIL12B mice | 120553 | C57BL/6 |
| B-hIL2RA mice | 110066 | C57BL/6 |
| B-hIL2RB mice | 110737 | C57BL/6 |
| B-hIL2RG mice | 110087 | C57BL/6 |
| B-hIL33 mice | 110055 | C57BL/6 |
| B-hIL36R mice | 110084 | C57BL/6 |
| B-hIL4 mice | 110064 | C57BL/6 |
| B-hIL4/hIL4RA mice | 120551 | C57BL/6 |
| B-hIL4/hIL4RA/hIL13 mice | 131037 | C57BL/6 |
| B-hIL4RA Mice | 110052 | C57BL/6 |
| B-hIL6/hIL6R mice | 120557 | C57BL/6 |
| B-hIL9R mice | 110761 | C57BL/6 |
| B-hPCSK9 mice | 110928 | C57BL/6 |
| B-hTNFA mice | 110002 | C57BL/6 |
| B-hTNFA/hIL17A mice | 120548 | C57BL/6 |
| B-hTNFA/hTNFR2 mice | 120749 | C57BL/6 |
| B-hTNFR2 mice | 110032 | C57BL/6 |
