Cytokines play an important role in regulating the body’s immune, hematopoietic, nervous, and endocrine systems. Cytokine antibodies in drug development have demonstrated positive clinical significance for treating autoimmune and other inflammatory diseases. The mechanisms and signal pathways of cytokines in the body are complex. Backed by detailed investigation and careful design, Biocytogen presents a series of mice models for preclinical evaluation of immunotherapy drugs with humanized cytokines and their receptors.
Humanized Cytokines Mice
| Product | Product No | Background |
|---|---|---|
| B-hHGF mice | 110868 | C57BL/6 |
| B-hIL13 mice | 110058 | C57BL/6 |
| B-hIL15RA mice | 110112 | C57BL/6 |
| B-hIL1A mice | 110073 | C57BL/6 |
| B-hIL21R mice | 110766 | C57BL/6 |
| Product | Product No | Background |
|---|---|---|
| B-hCSF1R mice | 110035 | C57BL/6 |
| B-hIL10 mice | 110060 | C57BL/6 |
| B-hIL17A Mice | 110053 | C57BL/6 |
| B-hIL1B mice | 110075 | C57BL/6 |
| B-hIL1RAcP mice | 110072 | C57BL/6 |
| B-hIL2 mice | 110085 | C57BL/6 |
| B-hIL23A/hIL12B mice | 120553 | C57BL/6 |
| B-hIL2RA mice | 110066 | C57BL/6 |
| B-hIL2RB mice | 110737 | C57BL/6 |
| B-hIL2RG mice | 110087 | C57BL/6 |
| B-hIL33 mice | 110055 | C57BL/6 |
| B-hIL4 mice | 110051 | C57BL/6 |
| B-hIL4/hIL4RA mice | 120551 | C57BL/6 |
| B-hIL4RA Mice | 110052 | C57BL/6 |
| B-hIL6/hIL6R mice | 120557 | C57BL/6 |
| B-hTNFA mice | 110002 | C57BL/6 |
| B-hTNFA/hIL17A mice | 120548 | C57BL/6 |
| B-hTNFA/hTNFR2 mice | 120749 | C57BL/6 |
| B-hTNFR2 mice | 110032 | C57BL/6 |
