Cytokines play an important role in regulating the body’s immune, hematopoietic, nervous, and endocrine systems. Cytokine antibodies in drug development have demonstrated positive clinical significance for treating autoimmune and other inflammatory diseases. The mechanisms and signal pathways of cytokines in the body are complex. Backed by detailed investigation and careful design, Biocytogen presents a series of mice models for preclinical evaluation of immunotherapy drugs with humanized cytokines and their receptors.
Humanized Cytokines Mice
| Product | Product No | Background |
|---|---|---|
| B-hIL10 mice | 110060 | C57BL/6 |
| B-hIL17A Mice | 110053 | C57BL/6 |
| B-hIL1B mice | 110075 | C57BL/6 |
| B-hIL2 mice | 110085 | C57BL/6 |
| B-hIL23A/hIL12B mice | 120553 | C57BL/6 |
| B-hIL2RA mice | 110066 | C57BL/6 |
| B-hIL2RB mice | 110737 | C57BL/6 |
| B-hIL2RG mice | 110087 | C57BL/6 |
| B-hIL33 mice | C57BL/6 | |
| B-hIL4 mice | 110051 | C57BL/6 |
| B-hIL4/IL4RA mice | 120551 | C57BL/6 |
| B-hIL4RA Mice | 110052 | C57BL/6 |
| B-hIL6/hIL6R mice | 120550 | C57BL/6 |
| B-hTNFA mice | 110002 | C57BL/6 |
| B-hTNFA/hIL17A mice | 120548 | C57BL/6 |
