Investigating Inflammatory Disease using Humanized Cytokine Mice
Speaker: Clarke Gasper, Ph.D. Senior Business Development Manager, Biocytogen Boston We reviewed the range of cytokines associated with various autoimmune and allergy related diseases. Introduced various humanized cytokine mouse models that can be used in disease modeling. The inflammatory disease models we have developed includes asthma, atopic dermatitis, and psoriasis. Details of some typical readouts […]
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Advancing T cell Therapies Using B-hCD3 Mouse Models
Biocytogen’s humanized mice are rigorously designed and validated in the following ways to improve translation of CD3-targeting candidates: Expression (mRNA & flow cytometry), Immune cell frequency & maturation profiling and functional validation using reference antibodies whenever available.
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Genome Engineering in Accelerating Discovery and Preclinical Applications
Use of Biocytogen’s CRISPR-based Extreme Genome Editing technology improves the efficiency of large fragment knock-in by up to 10-20 fold, meaning we can generate targeted cell lines, mouse and rat models in industry-leading timelines with a 98% success rate.
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4th Annual Next Gen Immuno-Oncology Virtual Congress: Humanized Immune Checkpoint Mice Improve Translatability of Novel Immunotherapies
Biocytogen’s humanized CD3E & CD3EDG models allow for broader targeting of the entire CD3 complex with novel mono- & bispecific antibody therapeutics.
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AET Europe 2021: Powerful Engine for Therapeutic Antibody Discovery – RenMab/RenLite Immunoglobulin Humanized Mouse Platform
Learn more about Biocytogen’s established first and second generation of immunoglobulin humanized mouse platforms: RenMab and RenLite.
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FcRn Therapies 2021 Conference: Humanized Mouse Models to Assess the In Vivo Efficacy of Antibody Therapeutics
Learn about the powerful models of Humanized mouse in IL4/IL4RA and IL-17 mice in various in-vivo settings
Read moreWebinars Category
- Antibody Discovery
- Humanized Animal Models
- Others
