Basic Information

Strain Name
C57BL/6-Mcpt5tm1(iCre)Bcgen/Bcgen
Common Name
B-Mcpt5-iCre mice
Background
C57BL/6
Catalog Number
110138
NCBI Gene ID
Application
B-Mcpt5-iCre mice may be useful for generating mast cell-specific conditional mutations.
Related Genes
Mcpt5, also known as Cma1,chymase 1, mast cell

Description

Homozygous mice for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. 

Publications using B-Mcpt5-iCre mice

Shu, T., Liu, Y., Zhou, Y. et al. Inhibition of immunoglobulin E attenuates pulmonary hypertension. Nat Cardiovasc Res 1, 665–678 (2022). https://doi.org/10.1038/s44161-022-00095-9

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