Basic Information

Strain Name
C57BL/6-Eportm1(EGFP-iCre)/Bcgen
Stock Number
110880
Common Name
B-Epor-EGFP-iCre mice
NCBI Gene ID
Strain of origin
C57BL/6
Gene symbol and name
Epor, erythropoietin receptor
Chromosome
9
Coat color
Black
Dietary information
Growth and reproduction diet for experimental mice
Application

Function research of genes, Function research of erythrocytes

Expressed gene

iCre, improved cre recombinase

EGFP, enhanced green fluorescent protein

Site of expression
Erythrocytes

Gene editing strategy

Phenotype Analysis

The expression of EGFP and tdTomato in mouse erythrocytes was detected by flow cytometry. The majority of erythrocytes in the bone marrow of B-Epor-EGFP- iCre(Mut/+); Rosa26-CAG- tdTomato(Mut/+) mice were double positive cells of EGFP and tdTomato, while the granulocytes in bone marrow were single positive cells of tdTomato. The results were consistent with the results in the study, indicating that B-Epor-EGFP-iCre mice were designed and expressed successfully.