Basic Information
Strain Name
SD-Oxttm1(iCre)Bcgen/Bcgen
Stock Number
210501
Common Name
B-Oxt-iCre rats
Source/Investigator
Bcgen (Beijing Biocytogen Co., Ltd)
Related Genes
Oxt(oxytocin)
NCBI Gene ID
Background
SD Rat
Appearance
White
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Targeting Strategy
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The P2A-CRE coding sequence was inserted into a locus between exon 3 and 3 ‘UTR of the Oxt gene. The gene-modified mouse background was Sprague-Dawley.
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Details
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Genotyping Information
Primer Sequence (5’-3’) Tm(℃) Product size
(bp)B-CR-025-Mut-F GGTGGCTGGACCAATGTGAAC 63 Mut:600 B-CR-025-WT-R GGCCGGGATTACCCCCTCAAC 59 B-CR-025-WT-F GGGCATCTGCTGTAGCCCGGG 62 WT: 646 Mut:1783
B-CR-025-WT-R GGCCGGGATTACCCCCTCAAC 59 -
References
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Harshaw C, Leffel J K, Alberts J R. Oxytocin and the warm outer glow: Thermoregulatory deficits cause huddling abnormalities in oxytocin-deficient mouse pups[J]. Hormones and behavior, 2018, 98: 145-158.
