Basic Information
Strain Name
C57BL/6J-Angptl4tm1(ANGPTL4)/Bcgen
Common Name
B-hANGPTL4 mice plus
Background
C57BL/6JNifdc
Catalog Number
112746
NCBI Gene ID
Related Genes
ARP4, FIAF, HARP, HFARP, NL2, PGAR, TGQTL, UNQ171, pp1158
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Targeting strategy
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Gene targeting strategy for B-hANGPTL4 mice plus.
The genome of mouse Angptl4 gene including 5’UTR and 3’UTR was replaced by human ANGPTL4 genome including 5’UTR and 3’UTR in B-hANGPTL4 mice plus. -
Protein expression analysis
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Strain specific analysis of ANGPTL4 gene expression in wild-type mice and B-hANGPTL4 mice plus by RT-PCR.
Mouse Angptl4 mRNA was detectable in fat of wild-type mice (+/+). Human ANGPTL4 mRNA was detectable in heterozygous B-hANGPTL4 mice plus but not in wild-type mice. -
Summary
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mRNA expression：
Mouse Angptl4 mRNA was detectable in fat of wild-type mice (+/+). Human ANGPTL4 mRNA was detectable in heterozygous B-hANGPTL4 mice but not in wild-type mice.
