Basic Information
Strain name
C57BL/6-Igs2tm1(IL26)Bcgen/Bcgen
Common name
B-hIL26 mice
Background
C57BL/6
Catalog number
112582
Aliases
AK155, IL-26
NCBI gene ID
-
Targeting strategy
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Gene targeting strategy for B-hIL26 mice.
The human IL26 gene was inserted into Hipp11 locus in B-hIL26 mice.
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mRNA expression analysis in humanized B-hIL26 mice
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Strain specific analysis of IL26 mRNA expression in wild-type C57BL/6 mice and B-hIL26 mice by RT-PCR. Colon RNA were isolated from wild-type C57BL/6 mice (+/+) and homozygous B-hIL26 mice (H/H), then cDNA libraries were synthesized by reverse transcription, followed by PCR with human IL26 primers. Human IL26 mRNA was only detectable in homozygous B-hIL26 mice.
