Basic Information
Strain Name
C57BL/6-Il6sttm1(IL6ST)Bcgen/Bcgen
Common Name
B-hIL6ST mice
Background
C57BL/6
Catalog number
111200
Aliases
CD130; GP130; HIES4; IMD94; STWS2; CDW130; HIES4A; HIES4B; IL-6RB; sGP130
NCBI Gene ID
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Protein expression analysis
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Strain specific IL6ST expression analysis in homozygous B-hIL6ST mice by ELISA. Serum was isolated from wild-type C57BL/6 mice (+/+) and homozygous B-hIL6ST mice (H/H) and analyzed by ELISA with species-specific IL6ST ELISA kit. Human IL6ST was exclusively detectable in homozygous B-hIL6ST mice but not in wild-type mice.
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mRNA expression analysis
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Strain specific analysis of IL6ST gene expression in wild-type C57BL/6 mice and B-hIL6ST mice by RT-PCR. Mouse Il6st mRNA was detectable only in lung and bladder of wild-type C57BL/6 mice. Human IL6ST mRNA was detectable only in homozygous B-hIL6ST mice but not in wild-type mice.
