Basic Information

Strain name
BALB/cCrSlcNifdc-Tslptm1(TSLP)Crlf2tm2(CRLF2)/Bcgen
Common Name
B-hTSLP/hTSLPR mice(C)
Background
BALB/cCrSlcNifdc
Catalog Number
112923
Aliases
TSLP: NA; CRLF2: CRL2Y, TSLPR
NCBI Gene ID
TSLP: 85480; TSLPR: 64109

Protein expression analysis-TSLP

Strain specific TSLP expression analysis in wild type BALB/c mice and heterozygous B-hTSLP mice(C) by ELISA. Calcipotriol (MC903) was dissolved in ethanol and topically applied on ears of wild type BALB/c mice and heterozygous B-hTSLP mice(C) for 7 days. Ear grinding supernatant from the two strains of mouse were analyzed by ELISA. Mouse TSLP was detectable in wild type BALB/c mice (+/+) and heterozygous B-hTSLP mice(C) (H/+). Human TSLP was only detectable in heterozygous B-hTSLP mice(C) but not in wild type mice.

 

Protein expression analysis-TSLPR

Strain specific TSLPR expression analysis in heterozygous B-hTSLP/hTSLPR mice(C) by flow cytometry. Blood were collected from wild-type BALB/c mice (+/+) and heterozygous B-hTSLP/hTSLPR mice(C) (H/+;H/+), and analyzed by flow cytometry with species-specific anti-TSLPR antibody. Mouse TSLPR was detectable in wild type BALB/c mice (+/+) and heterozygous B-hTSLP/hTSLPR mice(C) (H/+). Human TSLPR was only detectable in heterozygous B-hTSLP/hTSLPR mice(C) but not in wild type mice.

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