Basic Information
Strain name
C57BL/6N-Madcam1tm1(MADCAM1)Bcgen/Bcgen
Common name
B-hMADCAM1 mice
Background
C57BL/6N
Catalog number
111627
Aliases
MACAM1
NCBI gene ID
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mRNA expression analysis
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Strain specific analysis of MADCAM1 gene expression in wild-type C57BL/6 mice and B-hMADCAM1 mice by RT-PCR. Mouse Madcam1 mRNA was detectable only in splenocytes of wild-type C57BL/6 mice (+/+). Human MADCAM1 mRNA was detectable only in homozygous B-hMADCAM1 mice (H/H), but not in wild-type mice.
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Protein expression analysis
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Strain specific MADCAM1 expression analysis in homozygous B-hMADCAM1 mice by Immunohistochemistry (IHC). Mouse MADCAM1 was detectable in vascular endothelial cell of colon, small intestine and embryonic tissue in wild-type C57BL/6 mice (+/+). Human MADCAM1 was exclusively detectable in vascular endothelial cell of colon, small intestine and embryonic tissue of B-hMADCAM1 mice (H/H), but not in wild-type mice.
