Basic Information
Strain name
C57BL/6-Robo4tm1(ROBO4)/Bcgen
Common name
B-hROBO4 mice
Catalog number
111022
Background
C57BL/6N
Aliases
AOVD3, ECSM4, MRB(magic roundabout)
NCBI Gene ID
-
Targeting strategy
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The exons 1-9 of mouse Robo4 gene that encode the extracellular domain were replaced by human ROBO4 exons 1-9 in B-hROBO4 mice.
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Protein expression analysis
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Strain specific ROBO4 expression analysis in homozygous B-hROBO4 mice by western blot. Lung tissues were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hROBO4 mice (H/H), and analyzed by western blot with anti-ROBO4 antibody. Human ROBO4 was exclusively detectable in homozygous B-hROBO4 mice.
