Basic Information

Strain Name
NOD.CB17-PrkdcscidIl2rgtm1Kit tm1(V831M)/Bcgen
Common Name
B-NDG Kit W41 mice
Background
B-NDG
Catalog number
112914
Aliases 
PBT, SCFR, C-Kit, CD117, MASTC
NCBI Gene ID
Application Fields
This product can accept human hematopoietic stem cell transplantation without irradiation, making it suitable for research in the fields of blood and immunity.

mRNA expression analysis

Strain specific analysis of Kit mRNA expression in B-NDG mice and B-NDG Kit W41 mice by RT-PCR. Spleen and lung RNA was isolated from B-NDG mice (+/+) and heterozygous B-NDG Kit W41 mice (Mut/+), then cDNA libraries were synthesized by reverse transcription, followed by PCR with mouse Kit primers. Mouse Kit mRNA were detectable in B-NDG mice (+/+) and B-NDG Kit W41 mice (Mut/+). Sequence assays showed the B-NDG Kit W41 mice (Mut/+) consists of a G to A point mutation at amino acid 831.

Back to top