Basic Information
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Protein expression analysis in spleen
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Splenic T cells:
Strain specific ITGA1 expression analysis in homozygous B-hITGA1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hITGA1 mice (H/H), and analyzed by flow cytometry with species-specific anti-ITGA1 antibody. Human ITGA1 was exclusively detected in homozygous B-hITGA1 but not in wild-type mice. Mouse ITGA1 was detected only in wild-type mice.
Splenic B cells:
Strain specific ITGA1 expression analysis in homozygous B-hITGA1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hITGA1 mice (H/H), and analyzed by flow cytometry with species-specific anti-ITGA1 antibody. Human ITGA1 was exclusively detected in homozygous B-hITGA1 but not in wild-type mice. Mouse ITGA1 was detected only in wild-type mice.
Splenic NK cells:
Strain specific ITGA1 expression analysis in homozygous B-hITGA1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hITGA1 mice (H/H), and analyzed by flow cytometry with species-specific anti-ITGA1 antibody. Human ITGA1 was exclusively detected in homozygous B-hITGA1 but not in wild-type mice. Mouse ITGA1 was detected only in wild-type mice.
Splenic DCs:
Strain specific ITGA1 expression analysis in homozygous B-hITGA1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hITGA1 mice (H/H), and analyzed by flow cytometry with species-specific anti-ITGA1 antibody. Human ITGA1 was exclusively detected in homozygous B-hITGA1 but not in wild-type mice. Mouse ITGA1 was detected only in wild-type mice.
Splenic Monocytes:
Strain specific ITGA1 expression analysis in homozygous B-hITGA1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hITGA1 mice (H/H), and analyzed by flow cytometry with species-specific anti-ITGA1 antibody. Human ITGA1 was exclusively detected in homozygous B-hITGA1 but not in wild-type mice. Mouse ITGA1 was detected only in wild-type mice.
Splenic Macrophages:
Strain specific ITGA1 expression analysis in homozygous B-hITGA1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hITGA1 mice (H/H), and analyzed by flow cytometry with species-specific anti-ITGA1 antibody. Human ITGA1 was exclusively detected in homozygous B-hITGA1 but not in wild-type mice. Mouse ITGA1 was detected only in wild-type mice.
Splenic Neutrophils:
Strain specific ITGA1 expression analysis in homozygous B-hITGA1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hITGA1 mice (H/H), and analyzed by flow cytometry with species-specific anti-ITGA1 antibody. Human ITGA1 was not been detected in homozygous B-hITGA1 and wild-type mice. Mouse ITGA1 was detected only in wild-type mice.
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Protein expression analysis summary
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Strain specific ITGA1 expression analysis in homozygous B-hITGA1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hITGA1 mice (H/H), and analyzed by flow cytometry with species-specific anti-ITGA1 antibody. Human ITGA1 was exclusively detected in homozygous B-hITGA1 but not in wild-type mice. Mouse ITGA1 was detected only in wild-type mice.
