Basic Information
Strain Name
C57BL/6N-Ngaltm1(NGAL)/Bcgen
Common Name
B-hNGAL mice
Background
C57BL/6N
Catalog Number
112342
NCBI Gene ID
Related Genes
p25; 24p3; MSFI; LCN2
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Targeting strategy
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Gene targeting strategy for B-hNGAL mice.
The exons 1~6 of mouse Ngal gene that encode the full-length protein were replaced by human NGAL exons 1~6 in B-hNGAL mice. -
Protein expression analysis of F11R(JAM1) in platelet
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Strain specific NGAL expression analysis in homozygous B-hNGAL mice by ELISA. Serum was isolated from wild-type C57BL/6 mice (+/+) and homozygous B-hNGAL mice (H/H) and analyzed by ELISA with species-specific NGAL ELISA kit. Mouse NGAL was detectable in wild-type mice (A). Human NGAL was exclusively detectable in homozygous B-hNGAL mice but not in wild-type mice (B).
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Summary
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Protein expression analysis:
Mouse NGAL was detectable in wild-type mice. Human NGAL was exclusively detectable in homozygous B-hNGAL mice.
