Basic Information

Strain Name
C57BL/6N-Ifnar1tm1Bcgen/Bcgen
Common Name
B-Ifnar1 KO mice
Background
C57BL/6N
Catalog Number
111961
Related Gene
AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC
NCBI Gene ID

Targeting strategy

Gene targeting strategy for B-Ifnar1 KO mice. The exons 1~11 and 3’UTR of mouse Ifnar1 gene were knockout in B-Ifnar1 KO mice.

Protein expression analysis

IFNAR1 expression analysis in wild-type C57BL/6N and B-Ifnar1 KO mice by flow cytometry.  Splenocytes were collected from wild-type C57BL/6N and B-Ifnar1 KO mice. Mouse IFNAR1 was detectable in B cells, T cells, NK cells, DC cells, monocytes, macrophages and granulocytes of wild-type mice, but not in B-Ifnar1 KO mice.

Summary

Protein expression analysis:

Mouse IFNAR1 was knockout in B cells, T cells, NK cells, DC cells, monocytes, macrophages and granulocytes of B-Ifnar1 KO mice.

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