Basic Information

Strain Name
C57BL/6-Il36atm1BcgenIl36btm1BcgenIl36gtm1Bcgen/Bcgen
Common Name
B-Il36a/Il36b/Il36g KO mice
Background
C57BL/6
Catalog number
112455
Aliases
IL36A, FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), IL1F6, interleukin 36 alpha; IL36B, FIL1, FIL1-(ETA), FIL1H, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, interleukin 36 beta; IL36G, IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1, IL1RP2, interleukin 36 gamma

Targeting strategy

Gene targeting strategy for B-Il36a/Il36b/Il36g KO mice. The mouse full-length Il36a, Il36b and Il36g sequences were knocked out in B-Il36a/Il36b/Il36g KO mice.

mRNA expression analysis

Strain specific analysis of Il36a, Il36b and Il36g gene expression in wild type (WT) mice and B-Il36a/Il36b/Il36g KO mice by RT-PCR. Mouse Il36a, Il36b and Il36g mRNA was detectable only in lung of WT mice, but not in homozygous B-Il36a/Il36b/Il36g KO mice.

Summary

mRNA expression analysis:

Mouse Il36a, Il36b and Il36g mRNA was detectable only in lung of WT mice, but not in homozygous B-Il36a/Il36b/Il36g KO mice.

Back to top