Novel anti-4-1BB×PD-L1 bispecific antibody augments anti-tumor immunity through tumor-directed T-cell activation and checkpoint blockade
Jeong, S., Park, E., Kim, H-D. et al. Novel anti-4-1BB×PD-L1 bispecific antibody augments anti-tumor immunity through tumor-directed T-cell activation and checkpoint blockade. J Immunother Cancer. (2021). http://dx.doi.org/10.1136/jitc-2021-002428
Read more
A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions
Damelin, M., Bankovich, A., Bernstein, J. et al. A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions. Sci. Transl. Med. (2017). https://www.science.org/doi/10.1126/scitranslmed.aag2611
Read more
IBI112, a selective anti-IL23p19 monoclonal antibody, displays high efficacy in IL-23-induced psoriasiform dermatitis
Li, L., Wu, Z., Wu, M. et al. IBI112, a selective anti-IL23p19 monoclonal antibody, displays high efficacy in IL-23-induced psoriasiform dermatitis. Int. Immunopharmacol. (2020). https://doi.org/10.1016/j.intimp.2020.107008
Read more
Oncolytic adenovirus targeting TGF-β enhances anti-tumor responses of mesothelin-targeted chimeric antigen receptor T cell therapy against breast cancer
Li, Y., Fengjun, X., Zhang, D. et al. Oncolytic adenovirus targeting TGF-β enhances anti-tumor responses of mesothelin-targeted chimeric antigen receptor T cell therapy against breast cancer. Cell Immunol. (2020). https://doi.org/10.1016/j.cellimm.2020.104041
Read more
Anti-leukemia activities of selenium nanoparticles embedded in nanotube consisted of triple-helix β-d-glucan
Jin, Y., Cai, L., Yang, Q. et al. Anti-leukemia activities of selenium nanoparticles embedded in nanotube consisted of triple-helix β-d-glucan. Carb. Polymers. (2020). https://doi.org/10.1016/j.carbpol.2020.116329
Read more
HSP90 Inhibitor Ganetespib (STA-9090) Inhibits Tumor Growth in c-Myc-Dependent Esophageal Squamous Cell Carcinoma
Guan, L., Zou, Q., Liu, Q. et al. HSP90 Inhibitor Ganetespib (STA-9090) Inhibits Tumor Growth in c-Myc-Dependent Esophageal Squamous Cell Carcinoma. Onco Targets Ther. (2020). https://doi.org/10.2147/OTT.S245813
Read more
Cutting Edge: Inhibition of Glycogen Synthase Kinase 3 Activity Induces the Generation and Enhanced Suppressive Function of Human IL-10 + FOXP3 +-Induced Regulatory T Cells
Cheng, H., Wang, L., Yang, B. et al. Cutting Edge: Inhibition of Glycogen Synthase Kinas 3 Activity Induces the Generation and Enhanced Suppressive Function of Human IL-10+ FOXP3 +-Induced Regulatory T Cells. J Immunol. (2020). https://doi.org/10.4049/jimmunol.2000136
Read more
Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1
Yang, W., Zhang, K., Li, L. et al. Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1. J Exp Clin Cancer Res. (2021). DOI: 10.1186/s13046-021-01889-8
Read more
Licochalcone A improves the cognitive ability of mice by regulating T- and B-cell proliferation
Wu, Y., Zhu, J., Liu, H. et al. Licochalcone A improves the cognitive ability of mice by regulating T- and B-cell proliferation. Aging. (2021). https://doi.org/10.18632/aging.202704
Read more
R9AP is a functional receptor for Epstein-Barr virus infection in both epithelial cells and B cells
Zeng, M.-S., yan, l., Zhang, H. et al. R9AP is a functional receptor for Epstein-Barr virus infection in both epithelial cells and B cells. Biological Sciences. (2020). https://doi.org/10.21203/rs.3.rs-113641/v1
Read more